葡萄牙非包膜型和包膜型非b型侵袭性流感嗜血杆菌分离株的出现（1989 - 2001年）
Emergence of nonencapsulated and encapsulated non-b-type invasive Haemophilus influenzae isolates in Portugal (1989-2001).
作者信息
Bajanca Paula, Caniça Manuela
机构信息
Antibiotic Resistance Unit, National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.
出版信息
J Clin Microbiol. 2004 Feb;42(2):807-10. doi: 10.1128/JCM.42.2.807-810.2004.
Abstract
Phenotypes and genetic relatedness of invasive Haemophilus influenzae strains were evaluated from 1989 through 2001. Among 119 isolates, multidrug resistance decreased (from 50 to 0%), the level of H. influenzae serotype b (Hib) strains declined (from 81 to 16%), the level of noncapsulated strains rose (from 19 to 80%), and the first invasive H. influenzae serotype f strain was described. This study documents changes in invasive H. influenzae infections in Portugal, i.e., the emergence of non-type-b strains that are genetically diverse and unrelated to Hib.
摘要
1989年至2001年期间，对侵袭性流感嗜血杆菌菌株的表型和遗传相关性进行了评估。在119株分离株中，多重耐药性降低（从50%降至0%），b型流感嗜血杆菌（Hib）菌株水平下降（从81%降至16%），非荚膜菌株水平上升（从19%升至80%），并首次描述了侵袭性f型流感嗜血杆菌菌株。本研究记录了葡萄牙侵袭性流感嗜血杆菌感染的变化，即出现了遗传上不同且与Hib无关的非b型菌株。
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