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An aza-steroidal [17,16-c]pyrazole derivative: 2'-(p-fluorophenyl)-17a-aza-2'H-pyrazolo[4',3':16,17]-D-homoandrost-4-en-3-one.

作者信息

Thamotharan S, Parthasarathi V, Gupta Ranju, Jindal D P, Linden Anthony

机构信息

Department of Physics, Bharathidasan University, Tiruchirappalli 620 024, India.

出版信息

Acta Crystallogr C. 2004 Feb;60(Pt 2):o158-60. doi: 10.1107/S0108270103029159. Epub 2004 Jan 31.

DOI:10.1107/S0108270103029159
PMID:14767145
Abstract

The asymmetric unit of the title compound, C(26)H(30)FN(3)O, contains two crystallographically independent molecules, the core skeletons of which have the same absolute configuration and almost identical conformations, except for differences in the orientation of the p-fluorophenyl ring. The tetrahydropyridine ring adopts a half-chair conformation, while the cyclohexenone ring has a slightly distorted envelope conformation. The cyclohexane rings have chair conformations, sometimes slightly distorted. Intermolecular N-H.O, N-H.N and C-H.F interactions and an intramolecular C-H.N interaction are observed.

摘要

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