Kurihara M, Kumagai K, Yagishita S
Department of Pediatrics, Kanagawa Rehabilitation Center, Japan.
No To Shinkei. 1992 Sep;44(9):849-54.
We presented an autopsy case of a severely handicapped girl with sequelae of acute encephalopathy at 10 months old. The autopsy findings were diffuse leukomalacia in cerebral medulla, loss of nerve cells and marked gliosis in thalamus, leukomalacia with fibrous gliosis in central tegmental tracts, and marked fibrous gliosis of the cerebellar hemisphere. Purkinje cells were spared much more than granular cells. Hypertrophy of the nerve cells in the inferior olives were seen and the bundles of its efferent nerve fibers were thin. This case is worth reporting that she has suffered from brain damage about 8 years before, and the inferior olives are hypertrophic yet.
我们报告了一例10个月大患有急性脑病后遗症的严重残疾女孩的尸检病例。尸检结果显示,脑髓质有弥漫性脑白质软化,丘脑神经细胞缺失并伴有明显的胶质细胞增生,中央被盖束有脑白质软化并伴有纤维性胶质细胞增生,小脑半球有明显的纤维性胶质细胞增生。浦肯野细胞比颗粒细胞受损程度轻得多。可见下橄榄核神经细胞肥大,其传出神经纤维束变细。该病例值得报告,因为她在大约8年前曾遭受脑损伤,而下橄榄核至今仍呈肥大状态。