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2000 - 2001年伦敦当日检测诊所就诊人群的社会人口学特征、风险类别及艾滋病毒感染率

The sociodemographic profile, risk categories and prevalence of HIV infection among people attending a London same-day testing clinic, 2000-2001.

作者信息

Sinclair M, Bor R, Evans A, Glass D, Levitt D, Johnson M A

机构信息

Psychology Unit in HIV Medicine, 10th Floor, Royal Free Hospital NHS Trust, Pond Street, London NW3 2QG, UK.

出版信息

Int J STD AIDS. 2004 Jan;15(1):33-7. doi: 10.1258/095646204322637236.

Abstract

The objectives were to determine the sociodemographic profile, risk category, and prevalence of HIV infection amongst people attending a confidential clinic providing counselling, medical advice and results of HIV antibody testing on the same day of consultation. Data were collected on all 1749 individuals attending the same-day HIV testing clinic at the Royal Free Hospital, London and proceeding to HIV testing between June 2000 and May 2001. One thousand, one hundred and forty-eight men and 601 women (mean age 33.3 years) were tested for HIV antibodies. The primary risk for HIV infection was heterosexual contact (69.9%; 1224/1749) and homosexual contact (27.7%; 485/1749). Fifty individuals tested HIV-positive (42 men and eight women). HIV seroprevalence was 2.8% (50/1749) and was highest among men who reported risk through homosexual contact (6.2%; 30/485). The rates for heterosexual men and women were 1.8% (12/648) and 1.4% (8/576), respectively, though they were highest among Black Caribbean (12%; 3/25) and Black African attendees from sub-Saharan African countries (11.2%; 18/160). Of the total number attending the clinic, more than half (56%; 981/1749) had previously been tested and received a negative test result. Of the fifty HIV antibody-positive individuals, 26%, (13) had previously received a negative result and had all reported risk through homosexual contact. Thirty of the HIV antibody-positive individuals were asymptomatic, 14 were symptomatic and three were diagnosed with an AIDS-defining condition. Half of all HIV-positive attendees (51.2%; 22/43) presented at the time of testing with CD4 cell counts below the normal range (>400x10(6)/l). The high HIV seroprevalence among homosexual men, some of whom had previously tested negative, suggests that HIV prevention strategies used within this group may need to be reassessed. The continuing high HIV seroprevalence among individuals from African countries suggests that this population require specific targeting for HIV risk reduction and information on the advantages of early diagnosis and treatment.

摘要

研究目的是确定在一家提供咨询、医疗建议并能在咨询当天给出HIV抗体检测结果的保密诊所就诊人群的社会人口学特征、风险类别及HIV感染率。收集了2000年6月至2001年5月期间在伦敦皇家自由医院当日HIV检测诊所就诊并进行HIV检测的所有1749名个体的数据。对1148名男性和601名女性(平均年龄33.3岁)进行了HIV抗体检测。HIV感染的主要风险是异性接触(69.9%;1224/1749)和同性接触(27.7%;485/1749)。50人HIV检测呈阳性(42名男性和8名女性)。HIV血清阳性率为2.8%(50/1749),在报告通过同性接触有风险的男性中最高(6.2%;30/485)。异性恋男性和女性的感染率分别为1.8%(12/648)和1.4%(8/576),不过在加勒比黑人(12%;3/25)和撒哈拉以南非洲国家的非洲黑人就诊者中最高(11.2%;18/160)。在诊所就诊的总人数中,超过一半(56%;981/1749)之前曾接受检测且结果为阴性。在50名HIV抗体阳性个体中,26%(13人)之前检测结果为阴性,且均报告通过同性接触有风险。30名HIV抗体阳性个体无症状,14名有症状,3名被诊断患有艾滋病界定疾病。所有HIV阳性就诊者中有一半(51.2%;22/43)在检测时CD4细胞计数低于正常范围(>400×10⁶/l)。同性男性中较高的HIV血清阳性率,其中一些人之前检测为阴性,这表明该群体中使用的HIV预防策略可能需要重新评估。非洲国家个体中持续较高的HIV血清阳性率表明,需要针对这一人群专门开展降低HIV风险的工作,并提供关于早期诊断和治疗益处的信息。

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