Fonseca V, Desouza C, Asnani S, Jialal I
Section of Endocrinology, Department of Medicine, Tulane University Medical Center, New Orleans, Louisiana 70112, USA.
Endocr Rev. 2004 Feb;25(1):153-75. doi: 10.1210/er.2002-0034.
People with type 2 diabetes are disproportionately affected by cardiovascular disease (CVD), compared with those without diabetes. Traditional risk factors do not fully explain this excess risk, and other "nontraditional" risk factors may be important. This review will highlight the importance of nontraditional risk factors for CVD in the setting of type 2 diabetes and discuss their role in the pathogenesis of the excess CVD morbidity and mortality in these patients. We will also discuss the impact of various therapies used in patients with diabetes on nontraditional risk factors.
与非糖尿病患者相比，2型糖尿病患者受心血管疾病（CVD）的影响更为严重。传统危险因素并不能完全解释这种额外的风险，其他“非传统”危险因素可能很重要。本综述将强调2型糖尿病背景下非传统CVD危险因素的重要性，并讨论它们在这些患者CVD发病率和死亡率过高的发病机制中的作用。我们还将讨论糖尿病患者使用的各种疗法对非传统危险因素的影响。
