Chau G K, Dilly S A, Sheard C E, Rostron C K
St George's Hospital & Medical School, London.
Br J Ophthalmol. 1992 Nov;76(11):646-50. doi: 10.1136/bjo.76.11.646.
Deep lamellar keratoplasty on air involves injecting air into the corneal stroma to expand it to several times its normal thickness. This method is designed to facilitate dissection of the deep stroma and reduce the risk of perforation of Descemet's membrane when carrying out deep lamellar keratoplasty. We have modified the technique by using prelathed freeze-dried donor tissue and report our results in a series of patients with corneal stromal scarring owing to a variety of corneal problems, namely, keratoconus, pterygium, and herpes zoster ophthalmicus. All patients achieved best corrected postoperative visual acuity of 6/12 or better without problems associated with graft failure or rejection. Histopathological examination of corneal tissue following air injection showed surgical emphysema within the cornea and separation of deep stromal fibres from the underlying Descemet's membrane.
气体辅助深板层角膜移植术是向角膜基质内注入气体，使其扩张至正常厚度的数倍。该方法旨在便于进行深基质层的剥离，并降低在实施深板层角膜移植术时后弹力层穿孔的风险。我们采用预先车床加工的冻干供体组织对该技术进行了改良，并报告了一系列因各种角膜问题（即圆锥角膜、翼状胬肉和带状疱疹性眼病）导致角膜基质瘢痕患者的治疗结果。所有患者术后最佳矫正视力均达到6/12或更好，且未出现与植片失败或排斥相关的问题。气体注入后角膜组织的组织病理学检查显示角膜内存在手术性气肿，深层基质纤维与下方的后弹力层分离。
