Ding Y, Tian R H, Kinjo J, Nohara T, Kitagawa I
Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
Chem Pharm Bull (Tokyo). 1992 Nov;40(11):2990-4. doi: 10.1248/cpb.40.2990.
Three new oleanene glycosides, sophoraflavosides II-IV (2-4) were isolated together with sophoraflavoside I (1) as the corresponding methyl ester forms from Sophorae Radix, the fresh roots of Sophora flavescens AITON (Leguminosae). Their structures have been elucidated as oxytrogenin 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->2)-beta -D- glucuronopyranoside (2), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->2)-beta -D-glucuronopyranosyl oxytrogenin 22-O-alpha-L-arabinopyranoside (3) and 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->2)-beta -D-glucuronopyranosyl oxytrogenin 22-O-beta-D-glucopyranosyl-(1-->2)-alpha-L-arabinopyranoside (4), along with unambiguous characterization as 3 beta,22 beta,24-trihydroxyolean-12-en-29-oic acid for their sapogenol, named oxytrogenin (5) on the bases of chemical reactions and spectral analyses.
从豆科植物苦参（Sophora flavescens AITON）的新鲜根苦参中分离得到了三种新的齐墩果烷糖苷，即槐黄酮苷II-IV（2-4），以及相应甲酯形式的槐黄酮苷I（1）。通过化学反应和光谱分析，确定了它们的结构分别为氧化羟基羽扇豆醇3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-吡喃半乳糖基-(1→2)-β-D-葡萄糖醛酸吡喃糖苷（2）、3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-吡喃半乳糖基-(1→2)-β-D-葡萄糖醛酸吡喃糖基氧化羟基羽扇豆醇22-O-α-L-阿拉伯吡喃糖苷（3）和3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-吡喃半乳糖基-(1→2)-β-D-葡萄糖醛酸吡喃糖基氧化羟基羽扇豆醇22-O-β-D-吡喃葡萄糖基-(1→2)-α-L-阿拉伯吡喃糖苷（4），同时明确了它们的皂苷元为3β,22β,24-三羟基齐墩果-12-烯-29-酸，命名为氧化羟基羽扇豆醇（5）。
