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[明斯克人群中ABO和恒河猴系统的基因和表型分布]

[Geno- and phenotypic distribution by the ABO and Rhesus systems in the population of Minsk].

作者信息

Tolochko G V, Ivanov L V

出版信息

Genetika. 1978 Mar;14(3):532-5.

PMID:147798
Abstract

The distribution of blood groups of the ABO system is different in the rhesus-positive and rhesus-negative subpopulations. An increasing frequency of the phenotype A2 in the rhesus-negative subpopulation is observed. The calculation of the gene frequency reveals a deficiency of genes A1 and O, and the increasing frequency of genes A2 and B in the rhesus-negative part of the population. On the whole for the inhabitants of Minsk the ratio of the phenotypes A2/A1 differs significantly from the corresponding index for the republic as a whole, which is the evidence of a significant migration of the population in the capital of Byelorussia. The observed correlative dependences in the distribution of the genes of ABO system and of the rhesus system permit to recommend the accomplishment of a scientific search between the hereditary pathology and the susceptibility to different diseases and blood groups taking into consideration the rhesus appurtenance of the populations studied.

摘要

ABO血型系统在恒河猴阳性和恒河猴阴性亚群中的分布有所不同。在恒河猴阴性亚群中观察到A2表型的频率不断增加。基因频率的计算表明,在人群的恒河猴阴性部分中,A1和O基因缺乏,而A2和B基因的频率增加。总体而言,明斯克居民的A2/A1表型比例与整个共和国的相应指标有显著差异,这证明了白俄罗斯首都人口的大量迁移。在ABO系统基因和恒河猴系统基因分布中观察到的相关依赖性,使得我们可以建议在考虑所研究人群的恒河猴属性的情况下,对遗传病理学与不同疾病易感性和血型之间进行科学研究。

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