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[I型和III型膜增生性肾小球肾炎的临床与病理特征]

[Clinical and pathological features of type I and III membranoproliferative glomerulonephritis].

作者信息

Chen H P, Li L S, Bai X Y

机构信息

Department of Nephrology, Jinling Hospital, Nanjing.

出版信息

Zhonghua Nei Ke Za Zhi. 1992 May;31(5):293-6, 318.

PMID:1478129
Abstract

Analysis and comparisons were made between the clinical and pathological data obtained from 42 cases of type I and 17 cases of type III membranoproliferative glomerulonephritis (MPGN). It was shown that type I MPGN differed from type III remarkably in following respects: (1) Nephrosis was a salient feature of type III while hypertension, impairment of renal function and hematuria were more common in type I. (2) Pathological glomerular sclerosis, tubular interstitial changes and crescents formation occurred frequently in type I but not in type III. (3) Long term prognosis for type III was much better than type I. It is concluded the type III MPGN is a distinct clinical entity which differs from the classical type I MPGN in many aspects.

摘要

对42例I型和17例III型膜增生性肾小球肾炎(MPGN)的临床和病理数据进行了分析和比较。结果显示,I型MPGN与III型在以下方面有显著差异:(1)肾病是III型的突出特征,而高血压、肾功能损害和血尿在I型中更为常见。(2)I型常出现病理性肾小球硬化、肾小管间质改变和新月体形成,而III型则无。(3)III型的长期预后远优于I型。结论是,III型MPGN是一种独特的临床实体,在许多方面不同于经典的I型MPGN。

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