Kass D A
Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD 21205.
Eur Heart J. 1992 Nov;13 Suppl E:57-64. doi: 10.1093/eurheartj/13.suppl_e.57.
Methods to obtain pressure-volume loops in humans and their application to clinical diagnosis and treatment of cardiac disease are discussed. The method employs a conductance catheter, micromanometer, and inferior vena caval balloon occluder to reversibly and rapidly vary venous return. Multiple cardiac cycles measured during this manoeuvre are used to derive a variety of systolic and diastolic function indices, as well as estimates of vascular loading, and cardiac energetics. Strengths and weaknesses of the method as well as pressure-volume indexes themselves are briefly discussed. Lastly, three clinical examples are presented which serve to demonstrate how pressure-volume analysis can provide useful clinical information regarding diagnosis and/or treatment in subjects with heart failure symptoms.
本文讨论了在人体中获取压力-容积环的方法及其在心脏病临床诊断和治疗中的应用。该方法采用电导导管、微压计和下腔静脉球囊阻塞器来可逆且快速地改变静脉回流。在此操作过程中测量的多个心动周期用于得出各种收缩和舒张功能指标，以及血管负荷和心脏能量学的估计值。简要讨论了该方法以及压力-容积指标本身的优缺点。最后，给出了三个临床实例，以说明压力-容积分析如何能够为有心力衰竭症状的受试者提供有关诊断和/或治疗的有用临床信息。
