Spiliotis J, Scopa C D, Kyriakopoulou D, Pitsis A, Melachrinou M, Tzoracoleftherakis E, Androulakis J
Department of Surgery, University of Patras, Medical School, Greece.
Eur J Surg Oncol. 1992 Dec;18(6):580-4.
Benign or malignant smooth muscle tumors of the gastrointestinal tract are uncommon. The diagnostic and therapeutic approaches vary depending on the histological behavior of these neoplasms. Between 1981 and 1991, 32 patients with gastrointestinal tumors were treated at the Department of Surgery of the University of Patras. There were 16 females and 16 males. The mean age at the time of diagnosis was 61.9 years (range 22-83 years). Eighty-one per cent of the tumors were discovered in asymptomatic patients by a variety of diagnostic studies. Fifty-six per cent of tumors were located in the stomach, 38% in the small intestine and 6% in the colon. Leiomyomas made up 71.8% of these tumors and were treated by conservative excision. The malignant smooth muscle tumors were treated by radical excision in four cases and conservative excision in one case. The 5-year survival rate was 85% for leiomyomas and 0% for malignant smooth muscle tumors. There is widespread agreement that wide resection of the lesion is the appropriate treatment for these tumors. The size and mitotic activity of these tumors remain the most important diagnostic parameters and prognostic factors.
胃肠道的良性或恶性平滑肌肿瘤并不常见。诊断和治疗方法因这些肿瘤的组织学行为而异。1981年至1991年间，帕特雷大学外科治疗了32例胃肠道肿瘤患者。其中女性16例，男性16例。诊断时的平均年龄为61.9岁（范围22 - 83岁）。81%的肿瘤是通过各种诊断研究在无症状患者中发现的。56%的肿瘤位于胃，38%位于小肠，6%位于结肠。平滑肌瘤占这些肿瘤的71.8%，采用保守性切除治疗。恶性平滑肌肿瘤4例采用根治性切除，1例采用保守性切除。平滑肌瘤的5年生存率为85%，恶性平滑肌肿瘤为0%。人们普遍认为，广泛切除病变是这些肿瘤的适当治疗方法。这些肿瘤的大小和有丝分裂活性仍然是最重要的诊断参数和预后因素。
