Loseva M I, Shpagina L A, Lisukov I A, Ziubina L Iu, Kovynev I B
Gematol Transfuziol. 1992 May-Jun;37(5-6):16-20.
Significant changes have been recorded in the concentration of sulfhydryl groups, histidine, lipoproteins, catalase activity, saponin resistance, and kinetics of chemiluminescent responses of red blood cells in lymphoma patients. Lymphosarcoma is characterized by changes in the structure and function of red blood cells at the early stage of the process, whereas in lymphogranulomatosis changes are observed with the disease progressing, when pronounced signs of tumor intoxication are noted and anemia is present. In lymphosarcoma patients an increase of peripheral blood mononuclears is recorded which expresses the erythroid differentiating antigens with the use of monoclonal antibodies against glycophorin A (ZAE-3) and human erythroblast antigen AG-EB (HAE-9). In lymphogranulomatosis patients it was not detected.
淋巴瘤患者红细胞中巯基、组氨酸、脂蛋白、过氧化氢酶活性、皂苷抗性及化学发光反应动力学的浓度已记录到显著变化。淋巴肉瘤的特征是在病程早期红细胞的结构和功能发生变化，而在淋巴肉芽肿病中，随着疾病进展，当出现明显的肿瘤中毒迹象且存在贫血时会观察到变化。在淋巴肉瘤患者中，使用抗血型糖蛋白A（ZAE - 3）和人成红细胞抗原AG - EB（HAE - 9）的单克隆抗体记录到外周血单核细胞增加，其表达红系分化抗原。在淋巴肉芽肿病患者中未检测到这种情况。
