Fowler J F, Skinner S M, Belsito D V
Department of Medicine, University of Louisville, KY.
J Am Acad Dermatol. 1992 Dec;27(6 Pt 1):962-8. doi: 10.1016/0190-9622(92)70295-q.
Formaldehyde resins have been used to impart wrinkle resistance to clothing fabrics since 1926. After several patients with positive patch tests to formaldehyde resins had been examined, a study was undertaken of the records of all patch tests performed at the University of Louisville Patch Test Clinic and the Allergy Section of the Skin and Cancer Clinic of New York University Medical Center from January 1988 through April 1990 to determine the prevalence of positive patch-test reactions to formaldehyde-based textile resins and the clinical and demographic patterns associated with textile resin allergy.
Seventeen patients were identified at the two centers. Twelve were allergic to formaldehyde as well as to formaldehyde textile resins. Several clinical patterns were found, including accentuation of dermatitis in areas of tight clothing, primary occurrence in clothing-covered areas, and a chronic recalcitrant course. Ethylene urea melamine formaldehyde resin was the best screening agent with 14 definite positive reactions and one equivocal reaction.
Formaldehyde textile resin allergy is more common than has been previously recognized. Patch testing with one or more formaldehyde textile resins is indicated in patients with a particular pattern of dermatitis.
自1926年以来，甲醛树脂一直被用于赋予服装面料抗皱性能。在检查了几名对甲醛树脂斑贴试验呈阳性的患者后，对路易斯维尔大学斑贴试验诊所和纽约大学医学中心皮肤与癌症诊所过敏科在1988年1月至1990年4月期间进行的所有斑贴试验记录进行了研究，以确定对甲醛基纺织树脂斑贴试验阳性反应的患病率以及与纺织树脂过敏相关的临床和人口统计学模式。
在这两个中心共识别出17名患者。其中12名患者对甲醛以及甲醛纺织树脂过敏。发现了几种临床模式，包括紧身衣物覆盖区域皮炎加重、主要发生在衣物覆盖区域以及慢性顽固性病程。乙烯脲三聚氰胺甲醛树脂是最佳筛查剂，有14例明确阳性反应和1例可疑反应。
甲醛纺织树脂过敏比之前认为的更为常见。对于有特定皮炎模式的患者，建议使用一种或多种甲醛纺织树脂进行斑贴试验。
