Worster A S, Ghent C N
Department of Medicine, University Hospital, London, Ontario, Canada.
J Clin Gastroenterol. 1992 Oct;15(3):222-4. doi: 10.1097/00004836-199210000-00009.
Two patients, after ABO-incompatible liver transplant, developed a picture of chronic cholestasis that was associated with unique ductular appearances within the donor graft on retrograde cholangiography. We believe that the appearance of progressive ductular ectasia within liver grafts indicates a specific immunologically mediated injury to ductular epithelium, probably because of ductular epithelial expression of ABH antigens.
两名患者在进行ABO血型不相容肝移植后,出现了慢性胆汁淤积的症状,逆行胆管造影显示供体移植物内有独特的小胆管表现。我们认为,肝移植物内进行性小胆管扩张的出现表明小胆管上皮受到了一种特定的免疫介导损伤,可能是由于小胆管上皮表达ABH抗原所致。