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[三尖瓣细菌性心内膜炎的外科治疗]

[Surgical treatment of bacterial endocarditis of the tricuspid valve].

作者信息

Rózycka-Chrzanowska B, Werner B, Rawczyńska-Englert I, Lastowiecka E, Mészáros J, Janion M

机构信息

Klinika Wad Serca Instytutu Kardiologii, Warszawa.

出版信息

Kardiol Pol. 1992 Sep;37(9):152-5.

PMID:1479772
Abstract

We present a rare case of bacterial endocarditis of tricuspid valve caused by temporary intracardiac pacing. The 48-year old male patient developed complete a-v block during the 1st day of acute inferior myocardial infarction. Intracardiac electrode was inserted for temporary pacing. After 4 days signs of bacterial endocarditis developed. Patient was markedly febrile, moderate tachycardia with gallop rhythm and systolic murmur of tricuspid valve insufficiency were present. Dullness to percussion was audible at the base of right lung. Hepato- and splenomegaly appeared during the second month of hospitalization. Laboratory tests revealed: elevated ESR, leukocytosis with a shift to the left, several blood cultures were positive to Staphylococcus aureus. On repeated chest X-ray patchy infiltrates with thin-walled translucent pools were visible. Transthoracic and transoesophageal++ echocardiography provided more precise informations. Bacterial vegetations were visualised on the tricuspid valve. Coronary angiography revealed proximal occlusion of the right coronary artery and 75-80% stenosis of the left circumflex artery. Antibacterial treatment guided by blood cultures was begun: vancomycin combined with netilmycin, then tienamycin and diflucan--after 10 weeks treatment was decided to be unsuccessful and the decision about surgical treatment was made. In extracorporeal circulation posterior left leaflet together with granular bacterial growths was excised. Septal and anterior leaflets were found normal. Cultures made of excised tissue were positive for Staphylococcus aureus and subsequent treatment with fluoroquinolones gave satisfactory result. Postoperative echocardiography revealed only small tricuspid valve insufficiency. Coronary by-pass surgery was performed later because of the high risk of simultaneous operation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们报告一例罕见的由临时心内起搏引起的三尖瓣细菌性心内膜炎病例。该48岁男性患者在急性下壁心肌梗死的第一天出现完全性房室传导阻滞。插入心内电极进行临时起搏。4天后出现细菌性心内膜炎的症状。患者高热,有中度心动过速伴奔马律,存在三尖瓣关闭不全的收缩期杂音。右肺底部叩诊呈浊音。住院第二个月出现肝脾肿大。实验室检查显示:血沉升高,白细胞增多并左移,多次血培养对金黄色葡萄球菌呈阳性。再次胸部X线检查可见片状浸润影及薄壁半透明区。经胸和经食管超声心动图提供了更精确的信息。在三尖瓣上可见细菌性赘生物。冠状动脉造影显示右冠状动脉近端闭塞,左旋支动脉狭窄75 - 80%。根据血培养结果开始抗菌治疗:万古霉素联合奈替米星,然后替考拉宁和氟康唑。10周后认为治疗失败,决定进行手术治疗。在体外循环下切除后叶连同颗粒状细菌生长物。发现间隔叶和前叶正常。切除组织的培养对金黄色葡萄球菌呈阳性,随后用氟喹诺酮类药物治疗取得满意效果。术后超声心动图仅显示轻度三尖瓣关闭不全。由于同期手术风险高,后来进行了冠状动脉搭桥手术。(摘要截短至250字)

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