Steigleder G K
Mod Probl Paediatr. 1976;20:102-17.
We have discussed some aspects of differential diagnosis of inflammatory processes of the facial skin. The disorders mentioned include: eczematous processes, rosacea-like dermatitis, steroid rosacea, acne, especially the diagnosis and therapy of cystic acne, psoriasis, atopic dermatitis, viral infection (Heck's disease) and circumscribed scleroderma versus systemic sclerosis and hemiatrophy of the face. Our own findings reveal that the cytocinetics in the psoriatic lesion differ fundamentally from other epidermal inflammatory processes, especially as the DNS synthesis time is prolonged. And so we consider psoriasis to be an inborn fault in the metabolism of epidermal and other cells, which is only provoked by secondary influences (drugs, allergic reactions, local traumas). To our surprise cytocinetics in atopic dermatitis do not significantly differ in the dermal infiltrate from subacute allergic contact dermatitis. Pigmentation of the face also suggests the possibility of mercury intoxication.
我们已经讨论了面部皮肤炎症性疾病鉴别诊断的一些方面。所提及的病症包括:湿疹样病变、酒渣鼻样皮炎、类固醇性酒渣鼻、痤疮,尤其是囊肿性痤疮的诊断和治疗、银屑病、特应性皮炎、病毒感染(赫克病)以及局限性硬皮病与系统性硬化症和面部偏侧萎缩的鉴别。我们自己的研究结果表明,银屑病皮损中的细胞动力学与其他表皮炎症性疾病有根本差异,尤其是DNA合成时间延长。因此,我们认为银屑病是表皮及其他细胞代谢的先天性缺陷,仅由继发因素(药物、过敏反应、局部创伤)诱发。令我们惊讶的是,特应性皮炎的细胞动力学在真皮浸润方面与亚急性过敏性接触性皮炎并无显著差异。面部色素沉着也提示汞中毒的可能性。