Tao X, Hong C J, Yu S, Chen B, Zhu H, Yang M
Department of Environmental Health, School of Public Health, Shanghai Medical University, China.
Sci Total Environ. 1992 Dec 15;127(1-2):57-67. doi: 10.1016/0048-9697(92)90469-9.
The problems that city environmental protection planners face are how important the air pollution exposures are in relation to chronic obstructive pulmonary disease (COPD) in local residents and which factor should be controlled most urgently. The purpose of our study is to determine the control priority among ambient sulphur dioxide (SO2) inhalable particulates (IP) and indoor use of coal to prevent COPD in residents of the city. Ambient air pollution is mainly from SO2 and IP(< 10 nm). Indoor air pollution is mainly from the use of coal for heating and/or cooking. Distribution of ambient SO2, and IP concentrations were described using a quartic trend surface simulation. When stratified by two extreme levels of ambient SO2 and IP and types of fuel used indoors, eight local area populations in four communities with different combinations of exposure levels were selected. In each community a local area population mostly using coal and one mostly burning gas was chosen. Chronic obstructive pulmonary diseases (COPD, ICD 490-493) including chronic bronchitis, asthma and emphysema, are a major cause of death in residents of Shanghai. The relationship between the three air pollution factors and their health effects were analyzed at the level of mortality (1978-1987, 232,459 person-years), prevalence of symptoms (12,037 persons) of COPD, lung function and non-specific immunologic function (514 women). The results show that indoor use of coal has stronger associations with health than estimated exposure to ambient SO2 or IP.
城市环境保护规划者面临的问题是,空气污染暴露对当地居民慢性阻塞性肺疾病(COPD)的影响有多重要,以及哪个因素最迫切需要得到控制。我们研究的目的是确定环境空气中二氧化硫(SO2)、可吸入颗粒物(IP)以及室内燃煤在预防该市居民患慢性阻塞性肺疾病方面的控制优先级。环境空气污染主要来自SO2和IP(<10纳米)。室内空气污染主要来自用于取暖和/或烹饪的燃煤。采用四次趋势面模拟描述环境SO2和IP浓度的分布情况。按照环境SO2和IP的两个极端水平以及室内使用的燃料类型进行分层,选取了四个社区中具有不同暴露水平组合的八个局部地区人群。在每个社区,分别选取了一个主要使用煤炭的局部地区人群和一个主要使用燃气的局部地区人群。慢性阻塞性肺疾病(COPD,国际疾病分类490 - 493),包括慢性支气管炎、哮喘和肺气肿,是上海居民的主要死因之一。在死亡率(1978 - 1987年,232,459人年)、慢性阻塞性肺疾病症状患病率(12,037人)、肺功能以及非特异性免疫功能(514名女性)等层面,分析了这三种空气污染因素与其健康影响之间的关系。结果显示,室内燃煤与健康的关联比估计的环境SO2或IP暴露更强。