Lindgren A, Nilsson-Ehle P, Norrving B, Johansson B B
Department of Neurology, University Hospital, Lund, Sweden.
Acta Neurol Scand. 1992 Dec;86(6):572-8. doi: 10.1111/j.1600-0404.1992.tb05489.x.
We determined plasma lipid and lipoprotein concentrations in 131 patients (95 males, 36 females, mean age 71 years) 6 months after acute stroke onset. Compared to a reference population, the alterations of plasma lipid concentrations in stroke patients were moderate. However, the stroke patients had higher levels of triglyceride and lipoprotein (a) and lower concentrations of cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol. Patients with different subtypes of stroke showed significant differences when compared with each other by analysis of covariance (with adjustment for age, sex, smoking, hypertension and diabetes). Patients with carotid or vertebral artery disease had the higher levels of cholesterol, triglyceride and apolipoprotein B, whereas high density lipoprotein triglyceride concentrations were higher in patients with cardioembolic infarcts.
我们测定了131例急性卒中发病6个月后的患者（95例男性，36例女性，平均年龄71岁）的血浆脂质和脂蛋白浓度。与参照人群相比，卒中患者血浆脂质浓度的变化较为温和。然而，卒中患者的甘油三酯和脂蛋白(a)水平较高，而胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇浓度较低。通过协方差分析（校正年龄、性别、吸烟、高血压和糖尿病），不同亚型卒中患者相互比较时显示出显著差异。颈动脉或椎动脉疾病患者的胆固醇、甘油三酯和载脂蛋白B水平较高，而心源性栓塞性梗死患者的高密度脂蛋白甘油三酯浓度较高。
