Astakhova V S, Panchenko L M, Gnatov V I
Arkh Patol. 1992;54(8):15-8.
Basing on cloning in vitro, colony-forming stromal cells (CFSC) of the bone marrow were studied in 66 children with a congenital dislocation of the hip. Degenerative processes in the bones of the hip joint were followed by a significant decrease of CFSC cloning. A direct correlation between the results of surgical treatment and cloning efficiency is established. Thus, the cloning efficiency may be used as a criterion for determining feasibility, time of surgery and its prognosis.
基于体外克隆技术，对66例先天性髋关节脱位患儿的骨髓集落形成基质细胞（CFSC）进行了研究。髋关节骨骼中的退行性病变伴随着CFSC克隆的显著减少。手术治疗结果与克隆效率之间建立了直接相关性。因此，克隆效率可作为确定手术可行性、手术时间及其预后的标准。
