Chandler H D, Woolf C J, Hepburn H R
Biochem J. 1978 Mar 1;169(3):559-65. doi: 10.1042/bj1690559.
A mechanism for the translocation of ions across biological membranes is proposed in which transconformational changes occur in the membrane-bound ion pump. In particular, it is suggested that such conformational changes are effected by means of the propagation of crystal defects in the form of edge-dislocation glide.
提出了一种离子跨生物膜转运的机制,其中膜结合离子泵发生跨构象变化。具体而言,有人认为这种构象变化是通过以刃型位错滑移形式的晶体缺陷传播来实现的。