Lunde N M, Messana J M, Swartz R D
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0364.
J Am Soc Nephrol. 1992 Nov;3(5):1092-7. doi: 10.1681/ASN.V351092.
Peritonitis remains a significant cause of morbidity in ESRD patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Staphylococcus species, Streptococcus species, and less commonly, gram-negative rods comprise the majority of isolated organisms. Other organisms, including unusual bacteria, fungi, and mycobacteria, comprise 5% or less of cases. Many of the uncommon causes of CAPD peritonitis have been reviewed, with special emphasis on antimicrobial therapy and whether catheter removal was required. The presumed third case of CAPD-associated peritonitis caused by Listeria monocytogenes is also described. In contrast to two other reported cases, our patient was not overtly immunosuppressed. L. monocytogenes infection should therefore be considered in CAPD patients with gram-positive rod peritonitis, even if immunocompetence is presumed.
腹膜炎仍然是接受持续非卧床腹膜透析(CAPD)的终末期肾病(ESRD)患者发病的一个重要原因。葡萄球菌属、链球菌属,以及较不常见的革兰氏阴性杆菌是分离出的主要病原体。其他病原体,包括不常见的细菌、真菌和分枝杆菌,占病例的5%或更少。许多CAPD相关性腹膜炎的罕见病因已被综述,特别强调了抗菌治疗以及是否需要拔除导管。本文还描述了推测为由单核细胞增生李斯特菌引起的第三例CAPD相关性腹膜炎病例。与其他两例报告病例不同,我们的患者没有明显的免疫抑制。因此,即使假定患者免疫功能正常,对于患有革兰氏阳性杆菌性腹膜炎的CAPD患者,也应考虑单核细胞增生李斯特菌感染。