关于一种与美沙酮相关的新型解痉化合物1,1-二苯基-3-二甲基氨基丁烯-1（A29）的研究，以及该化合物与强效镇痛药凯托米酮（A21）联合使用的研究。 - Suppr

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超能文献

Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21).

作者信息

PETERSEN P V

出版信息

Acta Pharmacol Toxicol (Copenh). 1951;7(1):51-64. doi: 10.1111/j.1600-0773.1951.tb02849.x.

DOI:10.1111/j.1600-0773.1951.tb02849.x

PMID:14829296

Abstract

摘要

相似文献

Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21).关于一种与美沙酮相关的新型解痉化合物1,1-二苯基-3-二甲基氨基丁烯-1（A29）的研究，以及该化合物与强效镇痛药凯托米酮（A21）联合使用的研究。

Acta Pharmacol Toxicol (Copenh). 1951;7(1):51-64. doi: 10.1111/j.1600-0773.1951.tb02849.x.

[Structural analogies and synergism of analgesic action. I. Determination of analgesic action with analgesic combinations and some types of structural analogues with spasmolytic properties after thermal stimulus].[镇痛作用的结构类比与协同作用。I. 热刺激后用镇痛组合及某些具有解痉特性的结构类似物测定镇痛作用]

Anesth Anal. 1956 Nov-Dec;13(5):848-78.

[Some phenomena of synergism. I. Associations of analgesics and of a spasmolytic considered as their structural analog].[协同作用的某些现象。I. 镇痛药与被视为其结构类似物的解痉药的联合作用]

C R Seances Soc Biol Fil. 1955 Feb;149(3-4):258-61.

Spasmolytic action of 6-dimethylamino-4,4-diphenyl-3-heptanone (dolophine), a synthetic analgesic.合成镇痛药6-二甲基氨基-4,4-二苯基-3-庚酮（度冷丁）的解痉作用

Fed Proc. 1947;6(1):345.

A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine and related basic amides. II. Comparative analgesic activity, acute toxicity and tolerance development in rats for R875, morphine, pethidine and methadone.新型强效镇痛药系列：右旋2:2-二苯基-3-甲基-4-吗啉代丁酰基吡咯烷及相关碱性酰胺。II. R875、吗啡、哌替啶和美沙酮对大鼠的镇痛活性比较、急性毒性及耐受性发展

J Pharm Pharmacol. 1958 Jan;10(1):14-21. doi: 10.1111/j.2042-7158.1958.tb10268.x.

[Polamidon as a spasmolytic and analgesic].[聚拉米东作为一种解痉镇痛药]

Med Klin. 1950 Apr 21;45(16):489-94.

[Structural analogies & synergy of analgesic action. III. Determination, after a mechanical stimulus, of the analgesic action of combinations of analgesics & various types of structural analogues endowed with spasmolytic properties].[镇痛作用的结构类比与协同作用。III. 机械刺激后，对镇痛药与具有解痉特性的各类结构类似物组合的镇痛作用的测定]

Anesth Analg (Paris). 1957 May-Jul;14(3):469-91.

Clinical pharmacokinetics of ketobemidone. Its bioavailability after rectal administration.凯托米酮的临床药代动力学。其直肠给药后的生物利用度。

Eur J Clin Pharmacol. 1981 Feb;19(3):217-23. doi: 10.1007/BF00561953.

Histamine release from human basophils and isolated rat mast cells induced by ketobemidone, pethidine and the spasmolytic A29.由酮苄胺、哌替啶和解痉药A29诱导的人嗜碱性粒细胞和分离的大鼠肥大细胞释放组胺。

Acta Pharmacol Toxicol (Copenh). 1982 Jan;50(1):78-80. doi: 10.1111/j.1600-0773.1982.tb00943.x.

[First clinical experience with the use of levadone (1-6-dimethylamine-4-4-diphenyl-4-heptanone bitartrate); new synthetic analgesic product].[左吗喃（1-6-二甲基胺-4-4-二苯基-4-庚酮酒石酸盐）的首次临床应用经验；新型合成镇痛药]

Acta Anaesthesiol Belg. 1951 Jan-Feb;2(1):49-58.

引用本文的文献

Clinical pharmacokinetics of ketobemidone. Its bioavailability after rectal administration.凯托米酮的临床药代动力学。其直肠给药后的生物利用度。

Eur J Clin Pharmacol. 1981 Feb;19(3):217-23. doi: 10.1007/BF00561953.

Patient-controlled analgesic therapy, Part III: pharmacokinetics and analgesic plasma concentrations of ketobemidone.患者自控镇痛疗法，第三部分：酮咯酸氨丁三醇的药代动力学和镇痛血浆浓度

Clin Pharmacokinet. 1982 May-Jun;7(3):252-65. doi: 10.2165/00003088-198207030-00005.

Clinical pharmacokinetics and oral bioavailability of ketobemidone.凯托米酮的临床药代动力学与口服生物利用度

Eur J Clin Pharmacol. 1980 Jan;17(1):45-50. doi: 10.1007/BF00561676.

Behavioural effects in rats of morphine and amphetamine and of a combination of the two drugs.吗啡、安非他命及二者组合对大鼠行为的影响。

Psychopharmacologia. 1970;16(4):305-12. doi: 10.1007/BF00404736.

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