Gareau R, Brisson G R, Dubé J, Caron C, Longuy V
Université du Québec à Trois-Rivières, Québec, Canada.
Cell Mol Biol (Noisy-le-grand). 1992 Aug-Sep;38(5-6):571-4.
It has been reported that natural antibodies alter aging RBCs, so increasing their vulnerability for removal from the blood stream. Results presented indicate that binding of anti-Gal, a natural antibody, to erythrocytes increases RBC rigidity in terms of microviscosity and deformability. Removal of RBCs from circulation could, at least in part, depend on these alterations.
据报道，天然抗体可改变衰老的红细胞，从而增加其从血流中被清除的易感性。所呈现的结果表明，天然抗体抗半乳糖（anti-Gal）与红细胞的结合会在微粘度和可变形性方面增加红细胞的刚性。红细胞从循环中被清除可能至少部分取决于这些改变。
