人混合淋巴细胞培养中的集落刺激因子（CSF）：对人和小鼠祖细胞的影响。
Colony stimulating factor (CSF) in human mixed lymphocyte cultures: effect on human and mouse progenitor cells.
作者信息
Gassel W D, Havemann K, von Manteuffel G E, Laukel H
出版信息
Exp Hematol. 1978 Apr;6(4):391-7.
Supernatants from human two-way MLC, poor and rich in monocytes, were tested for their ability to induce colony growth of human and mouse progenitor cells in semi solid agar. Colony stimulating factor (CSF), with activity in both systems, indicated that allogenic lymphocytes require monocytes to produce CSF. Whereas human marrow showed an early kinetics of production, the liberation of CSF active on mouse marrow cells exhibited a delayed kinetics. These results, combined with other evidence, suggest that human lymphocytes produce two different factors.
对富含和缺乏单核细胞的人双向混合淋巴细胞培养上清液进行检测，以评估其在半固体琼脂中诱导人和小鼠祖细胞集落生长的能力。在两个系统中均具有活性的集落刺激因子（CSF）表明，同种异体淋巴细胞需要单核细胞来产生CSF。虽然人骨髓呈现早期产生动力学，但对小鼠骨髓细胞有活性的CSF释放表现出延迟动力学。这些结果与其他证据相结合，提示人淋巴细胞产生两种不同的因子。
Zotero 插件