Normand H, Vargas E, Bordachar J, Benoit O, Raynaud J
Instituto Boliviano de Biologia de Altura, La Paz, Bolivia.
Int J Sports Med. 1992 Oct;13 Suppl 1:S40-2. doi: 10.1055/s-2007-1024588.
The question is: to what extent periodic breathing usually observed in translocated subjects at high altitude affects normal and polycythemic residents of high altitude? Standard sleep parameters, chest wall movements, temperature of ventilated gas and arterial O2 saturation (SaO2) were continuously recorded in 7 normal highlanders (mean hematocrit: 51%) and 14 polycythemic highlanders (mean hematocrit: 68%) during one night in La Paz, 3,850 m, Bolivia. The patterns of breathing instability were analysed by two ways: measuring duration of apneas and counting all the oscillations of SaO2 greater than 1%. Normal and polycythemic highlanders displayed a wide intersubject variability with regard to breathing instability, hence no significant difference in the total number of apneas and oscillations of SaO2 could be evidenced between the 2 groups. However, the longest apneas and the highest number of oscillations of SaO2 were found in the polycythemic highlanders.
在高海拔地区易地转移的人群中通常观察到的周期性呼吸在多大程度上会影响高海拔地区的正常居民和红细胞增多症居民？在玻利维亚拉巴斯海拔3850米处，对7名正常高原居民（平均血细胞比容：51%）和14名红细胞增多症高原居民（平均血细胞比容：68%）在一个晚上连续记录标准睡眠参数、胸壁运动、通气气体温度和动脉血氧饱和度（SaO2）。通过两种方式分析呼吸不稳定模式：测量呼吸暂停持续时间并计算所有大于1%的SaO2波动次数。正常高原居民和红细胞增多症高原居民在呼吸不稳定方面个体间差异很大，因此两组之间在呼吸暂停总数和SaO2波动次数上没有显著差异。然而，在红细胞增多症高原居民中发现了最长的呼吸暂停和最高的SaO2波动次数。
