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1976 - 1984年斯德哥尔摩县心肌梗死患者生存率的时间趋势

Time trends in survival from myocardial infarction in Stockholm County 1976-1984.

作者信息

Hammar N, Larsen F F, Sandberg E, Alfredsson L, Theorell T

机构信息

Department of Epidemiology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Int J Epidemiol. 1992 Dec;21(6):1090-6. doi: 10.1093/ije/21.6.1090.

Abstract

In Stockholm county, a rapid decline in mortality from acute myocardial infarction (AMI) was observed among middle-aged men in the early 1980s. In the present study survival among AMI patients from 1976 to 1984 was investigated in order to explore whether improvements in survival may have contributed to this decline. AMI patients aged 30-74 years (n = 16,108) were identified through a hospital discharge register. Deaths within one year of hospital admission were ascertained by means of linkage to the national cause of death register. Survival 1 year after hospital admission increased in both genders during the period 1981-1984, but among women there was no uniform trend over the whole study period. The estimated age-adjusted relative risk of death within one year after hospital admission for patients with a first infarction admitted to hospital in 1983-1984 as compared to in 1981-1982 was 0.88 for men and 0.79 for women. The causes of the observed increase in survival could not be determined from this study, but changes in medical intervention as well as diagnostic improvements may have been important. Improved survival may have contributed to about 30% of the decline in mortality from AMI among middle-aged men in Stockholm county during the early 1980s.

摘要

20世纪80年代初,在斯德哥尔摩县,观察到中年男性急性心肌梗死(AMI)死亡率迅速下降。在本研究中,对1976年至1984年期间AMI患者的生存率进行了调查,以探讨生存率的提高是否可能导致了这种下降。通过医院出院登记册确定了年龄在30 - 74岁的AMI患者(n = 16,108)。通过与国家死亡原因登记册联动来确定入院一年内的死亡情况。在1981 - 1984年期间,男女患者入院一年后的生存率均有所提高,但在整个研究期间,女性患者的生存率没有统一的趋势。与1981 - 1982年相比,1983 - 1984年首次梗死入院患者入院一年内的估计年龄调整后相对死亡风险,男性为0.88,女性为0.79。本研究无法确定观察到的生存率提高的原因,但医疗干预的变化以及诊断的改善可能起到了重要作用。生存率的提高可能促成了20世纪80年代初斯德哥尔摩县中年男性AMI死亡率下降的约30%。

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