Holmes A H, Trotman-Dickenson B, Edwards A, Peto T, Luzzi G A
Infectious Diseases Unit, Churchill Hospital, Oxford.
Q J Med. 1992 Nov-Dec;85(307-308):875-82.
An increased frequency of bacterial pneumonia occurs in HIV-infected individuals: however the development of bronchiectasis is not well recognized. We describe seven patients with HIV infection who developed chronic symptomatic lung disease, six with troublesome recurrent infective exacerbations. Bronchiectasis was demonstrated by computed tomography in five patients, and bronchial wall thickening was shown in a further two patients. The characteristics of the patients are described, and possible aetiological factors are discussed. As measures become available which prolong the later stages of HIV disease, bronchiectasis may become an increasing problem in this patient population. Early recognition and appropriate management may significantly alter morbidity in advanced HIV disease.
HIV 感染个体中细菌性肺炎的发生率增加:然而,支气管扩张的发生尚未得到充分认识。我们描述了 7 例发生慢性症状性肺部疾病的 HIV 感染患者,其中 6 例有反复发作的感染性加重症状。5 例患者经计算机断层扫描证实有支气管扩张,另外 2 例患者显示支气管壁增厚。描述了患者的特征,并讨论了可能的病因。随着延长 HIV 疾病晚期阶段的措施出现,支气管扩张在这一患者群体中可能会成为一个日益严重的问题。早期识别和适当管理可能会显著改变晚期 HIV 疾病的发病率。