Pattison J M, Reidy J F, Rafferty M J, Ogg C S, Cameron J S, Sacks S H, Williams D G
Department of Renal Medicine, Guy's Hospital, London.
Q J Med. 1992 Nov-Dec;85(307-308):883-8.
Renovascular disease is a common cause of end-stage renal failure in the elderly population. We assessed the role of percutaneous transluminal renal angioplasty in the treatment of patients with renal failure due to renovascular disease by analysing our results in 60 patients treated between 1982 and 1991. All the patients had a baseline serum creatinine level greater than 150 mumol/l; improvement in renal function was defined as a 20 per cent reduction in this level. Seventy-five angioplasty procedures were attempted on 70 arteries in 60 patients. There was an improvement in renal function in 24 patients (40 per cent), whilst six (10 per cent) showed deterioration. The most dramatic improvement was seen in a small group of patients who had suffered an acute deterioration in renal function prior to angioplasty. There was a low incidence of serious complications. Renovascular disease is an important reversible cause of chronic renal failure and should be investigated aggressively so that percutaneous transluminal renal angioplasty can be undertaken in selected patients.
肾血管疾病是老年人群终末期肾衰竭的常见病因。我们通过分析1982年至1991年间接受治疗的60例患者的结果，评估了经皮腔内肾血管成形术在治疗因肾血管疾病导致肾衰竭患者中的作用。所有患者的基线血清肌酐水平均高于150μmol/L；肾功能改善定义为该水平降低20%。对60例患者的70条动脉进行了75次血管成形术尝试。24例患者（40%）肾功能得到改善，而6例（10%）出现恶化。在血管成形术前肾功能急性恶化的一小部分患者中观察到了最显著的改善。严重并发症的发生率较低。肾血管疾病是慢性肾衰竭的一个重要可逆病因，应积极进行检查，以便在选定的患者中开展经皮腔内肾血管成形术。
