al-Hadrani A, Lavelle-Jones M, Kennedy N, Neill G, Sutton D, Cuschieri A
Department of Surgery, Ninewells Hospital and Medical School, Dundee, Scotland, U.K.
Ann Chir Gynaecol. 1992;81(4):351-3.
75SeHCAT scanning was evaluated as a means of detecting bile acid malabsorption in patients with postvagotomy diarrhoea. Seven day 75SeHCAT retention ratios were measured in five patients with unequivocal post-vagotomy diarrhoea. The results were compared with an age matched group of asymptomatic control patients (n = 4) each of whom had previously undergone truncal vagotomy and drainage and a further group of normal volunteers (n = 6). The median 75SeHCAT retention ratios in patients with post-vagotomy diarrhoea was 2% (range 0-9%). In contrast, the median 75SeHCAT retention ratios in asymptomatic controls was 29% (range 26-61%) and 28% (range 19-70%) in normal volunteers. These results demonstrate that there is gross bile salt malabsorption in patients with post-vagotomy diarrhoea and that 75SeHCAT scanning is an effective screening test in these patients.
对75硒-同型胆酸（75SeHCAT）扫描作为检测迷走神经切断术后腹泻患者胆汁酸吸收不良的一种方法进行了评估。测定了5例明确诊断为迷走神经切断术后腹泻患者的75SeHCAT七天潴留率。将结果与年龄匹配的无症状对照患者组（n = 4）进行比较，这些对照患者均曾接受过迷走神经干切断术和引流术，还与另一组正常志愿者（n = 6）进行了比较。迷走神经切断术后腹泻患者的75SeHCAT潴留率中位数为2%（范围0 - 9%）。相比之下，无症状对照患者的75SeHCAT潴留率中位数为29%（范围26 - 61%），正常志愿者为28%（范围19 - 70%）。这些结果表明，迷走神经切断术后腹泻患者存在严重的胆盐吸收不良，且75SeHCAT扫描是这些患者的一种有效筛查试验。
