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耶尔森菌关节炎的长期预后:临床和血清学研究结果

Long term prognosis in yersinia arthritis: clinical and serological findings.

作者信息

Herrlinger J D, Asmussen J U

机构信息

Medical Clinic, District Hospital, Rendsburg (a teaching hospital of Christian Albrechts University in Kiel), Germany.

出版信息

Ann Rheum Dis. 1992 Dec;51(12):1332-4. doi: 10.1136/ard.51.12.1332.

Abstract

Twenty two patients were followed up for a mean of 10.7 years after acute yersinia arthritis. Their clinical course, agglutination antibodies, antibodies against plasmid coded yersinia proteins, and laboratory parameters of inflammation were analysed. The clinical findings were unremarkable. Serum agglutinating antibodies against Yersinia enterocolitica were not found in any patient. Ten patients had no antibodies against plasmid coded bacterial proteins. Five patients showed IgG antibodies, one patient had an IgA and IgG result of questionable significance, and six patients had IgA and IgG antibodies in the immunoblot reaction. No evidence of systemic inflammation was found. The persistence of IgA or IgG antibodies, or both, did not have a discernible influence on the clinical course. The development of erosive changes in the sacroiliac joints occurred independently of yersinia infection.

摘要

22例患者在急性耶尔森菌关节炎后平均随访10.7年。分析了他们的临床病程、凝集抗体、针对质粒编码的耶尔森菌蛋白的抗体以及炎症的实验室参数。临床发现无异常。所有患者均未检测到抗小肠结肠炎耶尔森菌的血清凝集抗体。10例患者没有针对质粒编码的细菌蛋白的抗体。5例患者出现IgG抗体,1例患者的IgA和IgG结果意义存疑,6例患者在免疫印迹反应中出现IgA和IgG抗体。未发现全身炎症的证据。IgA或IgG抗体或两者的持续存在对临床病程没有明显影响。骶髂关节侵蚀性改变的发生与耶尔森菌感染无关。

相似文献

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Seronegative arthritis associated with serological evidence of Yersinia infection in Australia.
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本文引用的文献

2
Arthritis associated with Yersinia enterocolitica infection.与小肠结肠炎耶尔森菌感染相关的关节炎。
Acta Rheumatol Scand. 1969;15(3):232-53. doi: 10.3109/rhe1.1969.15.issue-1-4.32.
7
Ten-year follow-up study of patients with Yersinia arthritis.
Arthritis Rheum. 1988 Apr;31(4):533-7. doi: 10.1002/art.1780310410.

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