Nemunaitis J
Hematopoiesis Programme, Western Pennsylvania Cancer Institute, West Penn Hospital, Pittsburgh 15224.
Ann Med. 1992 Dec;24(6):439-44. doi: 10.3109/07853899209166992.
Haematopoietic colony stimulating factors (CSFs) stimulate the proliferation, differentiation and functional activity of myelocytes. Since approval of the use of these factors in patients with chemotherapy-induced neutropenia, patients undergoing autologous bone marrow transplantation (BMT) and patients with delayed engraftment after BMT, several other potential clinical uses have been described. Current and potential future clinical applications of CSFs will be reviewed.
造血集落刺激因子(CSF)可刺激骨髓细胞的增殖、分化和功能活性。自从批准将这些因子用于化疗引起的中性粒细胞减少症患者、接受自体骨髓移植(BMT)的患者以及BMT后植入延迟的患者以来,已描述了其他几种潜在的临床用途。本文将对CSF目前和未来潜在的临床应用进行综述。