Deletion (7)(p11p15) in a patient with Philadelphia-positive chronic myelogenous leukemia.

作者信息

Carrasco Juan J L, Otero Gómez A, García Miranda J L, Trujillo González M, Herrera Fernández M, Bello Hernández T

机构信息

Cytogenetics Service, Faculty of Medicine, University of La Laguna, Tenerife, Canary Islands, Spain.

出版信息

Cancer Genet Cytogenet. 1992 Dec;64(2):142-4. doi: 10.1016/0165-4608(92)90344-8.

We report a case of chronic myelogenous leukemia (CML) with a Philadelphia (Ph) chromosome. During the transformation phase of the disease, a del(7)(p11p15) and a +Ph were identified as additional chromosomal anomalies. We believe that loss of the segment 7p11-->p15 may play an important role in the progression of the disease.