Gur'ianov M I
Tobolsk Biological Research Station, Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, 626150, Tobolsk, Volcov St., 15. Russia.
Ross Fiziol Zh Im I M Sechenova. 2003 Dec;89(12):1529-37.
An ability for a forestalling regulation of contractility of the heart with calculation of the tendency of rhythm increasing was revealed under a gradual increasing of heart rhythm. A forestalling regulation of heart contractility occurs with rhythm assimilation at the cell level of the heart and irrespective of the influence of Frank-Starling law and neurohumoral factors on the work of the heart. A 5-10% increasing of heart rhythm is characterized by optimal rhythm assimilation. A 15-40% increasing of heart rhythm is not optimal and results in transformation of the rhythm. The following sequence of events take place in the process of transition from rhythm assimilation to rhythm transformation under a gradual increasing of heart rhythm: rhythm assimilation--rhythm by mechanical function--incomplete rhythm assimilation by electrical function-transformation of rhythm by electrical function.
在心率逐渐增加的情况下，发现了一种通过计算心率增加趋势来预先调节心脏收缩力的能力。心脏收缩力的预先调节发生在心脏细胞水平的节律同化过程中，且与Frank-Starling定律和神经体液因素对心脏工作的影响无关。心率增加5-10%的特征是最佳节律同化。心率增加15-40%并非最佳，会导致节律转变。在心率逐渐增加的情况下，从节律同化到节律转变的过程中会发生以下一系列事件：节律同化——机械功能的节律——电功能的不完全节律同化——电功能的节律转变。
