He B, Cohen R J
Harvard University-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge 02139.
IEEE Trans Biomed Eng. 1992 Nov;39(11):1179-91. doi: 10.1109/10.168684.
A new noninvasive approach has been developed to resolve spatially distributed cardiac electrical activity by measuring the surface Laplacian of the body surface potential. Computer simulations demonstrate the ability of the Laplacian map compared with the potential map to image spatially distributed dipole sources embedded in a semi-infinite volume conductor. Body surface Laplacian mapping has been implemented in human subjects utilizing dry bipolar Laplacian electrodes and compared with potential maps obtained using the central terminal of each bipolar Laplacian electrode. The body surface Laplacian ECG distribution was found to provide better spatial resolution than the body surface potential distribution. The body surface Laplacian map appears to resolve depolarization and repolarization of different regions of the heart. Further improvements of the body surface Laplacian mapping may permit noninvasive mapping of spatially distributed intracardiac events.
一种新的非侵入性方法已经被开发出来，通过测量体表电位的表面拉普拉斯算子来解析空间分布的心脏电活动。计算机模拟表明，与电位图相比，拉普拉斯图能够对嵌入半无限体积导体中的空间分布偶极源进行成像。体表拉普拉斯映射已在人体受试者中实施，使用干式双极拉普拉斯电极，并与使用每个双极拉普拉斯电极的中央终端获得的电位图进行比较。发现体表拉普拉斯心电图分布比体表电位分布具有更好的空间分辨率。体表拉普拉斯图似乎能够解析心脏不同区域的去极化和复极化。体表拉普拉斯映射的进一步改进可能允许对空间分布的心内事件进行非侵入性映射。
