Chunlertrith K, Sukeepaisarnjaroen W, Mairiang E, Laopaiboon V, Pairojkul C, Bhudhisawasdi V
Department of Medicine, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Thailand.
J Med Assoc Thai. 1992 Jun;75(6):341-9.
This prospective study aims to determine whether specific symptoms or group of symptoms could positively discriminate the etiology of patients who present with dyspepsia. Two hundred and eight patients were studied and 111, 55, 35 patients were classified as non-ulcer dyspepsia, peptic ulcer disease and hepatobiliary disease, respectively. All patients completed a structured history questionnaire by personal interview and completed investigation with complete blood count, stool examination, liver function test, HBsAg, HBsAb, ultrasonography of the abdomen and endoscopy. Variable of interest and variables of statistical significance by univariate analysis were put into discriminant function of logistic model for discrimination. The results suggest that anorexia and no periodicity of epigastric pain significantly discriminated non-ulcer dyspepsia from peptic ulcer disease and hepatobiliary disease, pain occurring before a meal or when the patient was hungry and nocturnal epigastric pain significantly discriminated peptic ulcer disease from hepatobiliary disease.
这项前瞻性研究旨在确定特定症状或症状组是否能够对出现消化不良症状的患者的病因做出阳性鉴别诊断。研究了208例患者，其中111例、55例、35例患者分别被归类为非溃疡性消化不良、消化性溃疡病和肝胆疾病。所有患者均通过个人访谈完成了一份结构化病史问卷，并完成了全血细胞计数、粪便检查、肝功能检查、乙肝表面抗原、乙肝表面抗体、腹部超声和内镜检查。将单因素分析中有意义的相关变量和有统计学意义的变量纳入逻辑模型判别函数进行判别。结果表明，厌食和上腹部疼痛无周期性可显著区分非溃疡性消化不良与消化性溃疡病和肝胆疾病，餐前或饥饿时出现的疼痛以及夜间上腹部疼痛可显著区分消化性溃疡病与肝胆疾病。
