Olubuyide I O, Atoba M A, Ayoola E A
Department of Medicine, University College Hospital, Ibadan, Nigeria.
Trop Geogr Med. 1989 Oct;41(4):337-40.
In a prospective study between January 1982 and December 1986, 402 patients with dyspepsia were seen at the gastroenterology clinic of the University College Hospital, Ibadan. The patients were evaluated using upper gastro-intestinal fibre-optic endoscopy in addition to laboratory and radiological examination. Out of these, 374 patients were later analysed for the present study. Of the group, 14% had peptic ulcers (duodenal ulcer 10.3%; gastric ulcer 3.7%); and 26.7% had mucosal inflammation of oesophagus and gastroduodenum. 55% had no lesion as observed by endoscopy. Our observation therefore indicates that most of the dyspeptic patients at Ibadan have non-ulcer dyspepsia. The pathogenesis of dyspepsia is briefly discussed.
在1982年1月至1986年12月的一项前瞻性研究中,伊巴丹大学学院医院胃肠病科门诊共接待了402例消化不良患者。除实验室检查和放射学检查外,还对这些患者进行了上消化道纤维内镜检查。其中,374例患者随后被纳入本研究进行分析。该组患者中,14%患有消化性溃疡(十二指肠溃疡10.3%;胃溃疡3.7%);26.7%患有食管及胃十二指肠黏膜炎症。55%的患者经内镜检查未发现病变。因此,我们的观察表明,伊巴丹的大多数消化不良患者患有非溃疡性消化不良。本文还简要讨论了消化不良的发病机制。