Zwijnenberg R J, Vulto A G, van Miert A S, Lumeij J T
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine and Sciences, University of Utrecht, The Netherlands.
J Vet Pharmacol Ther. 1992 Dec;15(4):364-78. doi: 10.1111/j.1365-2885.1992.tb01028.x.
Antibiotics and chemotherapeutics marketed for use in racing pigeons (Columba livia var. domestica) were evaluated by comparing the dosages and indications given by the manufacturers with the data obtained by pharmacokinetic, bacteriological and efficacy studies. This comparison showed that only three of the recommended dosages and indications of the 60 formulations marketed in The Netherlands are scientifically sound and in accordance with the literature. It is to be expected that the majority of the antimicrobials for pigeons will not satisfy the requirements for final registration as a pigeon therapeutic under the Dutch Veterinary Medicines Act of 1985. Several factors affecting drug availability are discussed, such as the different routes of administration and the influence of food. The public health aspects of the consumption of medicated pigeons is also discussed. Although there is no legislation with regard to this subject, a recommended withdrawal time of 10 days for the majority of the antimicrobials seems advisable.
通过将制造商给出的剂量和适应症与通过药代动力学、细菌学和疗效研究获得的数据进行比较,对市售的赛鸽(家鸽变种)用抗生素和化学治疗剂进行了评估。这种比较表明,在荷兰市场上销售的60种制剂中,只有三种推荐剂量和适应症在科学上是合理的,并且与文献一致。可以预期,大多数鸽子用抗菌药物将不符合1985年荷兰《兽药法》规定的作为鸽子治疗药物最终注册的要求。讨论了影响药物可获得性的几个因素,如不同的给药途径和食物的影响。还讨论了食用用药鸽子的公共卫生问题。尽管在这个问题上没有立法,但对于大多数抗菌药物,建议停药时间为10天似乎是明智的。