冠状动脉狭窄处的壁面切应力估计

Wall shear stress estimates in coronary artery constrictions.

作者信息

Back L H, Crawford D W

机构信息

Jet Propulsion Laboratory, California Institute of Technology, Pasadena 91109.

出版信息

J Biomech Eng. 1992 Nov;114(4):515-20. doi: 10.1115/1.2894104.

DOI:10.1115/1.2894104

PMID:1487905

Abstract

Wall shear stress estimates from laminar boundary layer theory were found to agree fairly well with the magnitude of shear stress levels along coronary artery constrictions obtained from solutions of the Navier Stokes equations for both steady and pulsatile flow. The relatively simple method can be used for in vivo estimates of wall shear stress in constrictions by using a vessel shape function determined from a coronary angiogram, along with a knowledge of the flow rate.

摘要

研究发现，根据层流边界层理论估算的壁面剪应力与通过求解纳维-斯托克斯方程得到的冠状动脉狭窄处稳定流和脉动流的剪应力水平大小相当吻合。这种相对简单的方法可用于体内狭窄处壁面剪应力的估算，即利用从冠状动脉血管造影确定的血管形状函数以及流速信息来进行估算。