Ortiz de Lejarazu R, Eiros J M, Almaraz A, Castrodeza J, Martín F J, Rodríguez Torres A
Servicio de Microbiología y Medicina Preventiva, Hospital Clínico y Facultad de Medicina, Valladolid.
Rev Clin Esp. 1992 Dec;191(9):468-72.
In order to determine the frequency of HIV seropositivity of sera from patients attending our hospital emergency department (ED) we used a HIV screening system based on the use of pooled sera. To determine the reliability of this marker we collect all ED serum samples during two different intervals of a week. From 577 sera analyzed by this method we detected 1.38% of HIV positive samples (95% confidence interval from 0.43% to 2.33%) with 74% benefit on reactives. We did not find significative differences between the rates of HIV seropositivity in the two period of analyzing (1.6% in October 1990 vs 1.2% in February 1991). The consistency of this method for anonymous HIV testing could be applied to a large number of samples from cohorts of expected low HIV prevalence rates and indirectly using this marker to control the spreading of HIV in a given population.
为了确定我院急诊科患者血清中HIV血清阳性的频率，我们使用了一种基于混合血清的HIV筛查系统。为了确定该标志物的可靠性，我们在一周的两个不同时间段收集了所有急诊科血清样本。通过这种方法分析的577份血清中，我们检测到1.38%的HIV阳性样本（95%置信区间为0.43%至2.33%），反应性样本的获益率为74%。我们未发现两个分析时间段的HIV血清阳性率之间存在显著差异（1990年10月为1.6%，1991年2月为1.2%）。这种用于匿名HIV检测的方法的一致性可应用于大量预期HIV流行率较低的队列样本，并间接使用该标志物来控制HIV在特定人群中的传播。
