Zumbro G L, Tillman L, Bailey A O, Treasure R L
Ann Thorac Surg. 1978 Jun;25(6):541-50. doi: 10.1016/s0003-4975(10)63606-5.
Ischemic contracture of the left ventricle ("stone heart") was studied utilizing a previously described stone heart model. Our studies suggest that beta-adrenergic blockade is not quantitatively as important as hypothermia in protecting ischemic myocardium. On the basis of reduced fibrillatory activity and a slight protective effect shown by electron microscopy, it would appear that combining propranolol with hypothermia may be superior to either used singly.
利用先前描述的“石心”模型对左心室缺血性挛缩（“石心”）进行了研究。我们的研究表明，在保护缺血心肌方面，β-肾上腺素能阻滞剂在数量上不如低温重要。基于纤颤活动减少以及电子显微镜显示的轻微保护作用，看来普萘洛尔与低温联合使用可能优于单独使用任何一种。
