Robb R M, Marchevsky A
Arch Ophthalmol. 1978 Jun;96(6):1039-42. doi: 10.1001/archopht.1978.03910050559014.
A pathological study of the lenses of 21 patients with Down's syndrome disclosed no distinctive abnormalities of the lens capsule, as had been reported previously. Five patients, 15 years of age or older, had focal cortical changes consistent with the characteristic flake-like opacities seen in patients with Down's syndrome after the first decade of life. Three patients with more extensive, visually significant lens opacities showed nonspecific cataractous changes. No abnormalities other than pathological artifacts were seen in the lenses of patients younger than 15 years of age.
一项针对21名唐氏综合征患者晶状体的病理学研究表明，晶状体囊并未出现如先前报道的明显异常。5名15岁及以上的患者出现了局灶性皮质改变，与唐氏综合征患者在10岁以后出现的典型片状混浊相符。3名晶状体混浊范围更广且具有明显视觉影响的患者表现出非特异性白内障改变。15岁以下患者的晶状体除病理假象外未见其他异常。
