[Treatment of blast crisis of chronic myeloid leukemia].

Up-date of chemotherapy in the accelerated and blastic phases of CGL has been done. Cytostatic therapy, even very intensive, remains ineffective in the eradication of pathological cellular clones as well as interferons therapy. The unique chance of being cured for a small cohort of patients with accelerated or blastic disease is allogeneic bone marrow transplantation. An effective treatment of these phases of CGL remains to be solved in the future.