Pedersen K, Christensen G W, Steffensen M, Schyum P, Johansen A K
Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Acta Vet Scand. 1992;33(4):297-303. doi: 10.1186/BF03547295.
The spread of lactic acid bacterial strains to the environment and to newborn piglets was investigated after feeding of such strains to sows. Rifampicin resistant bacterial strains were fed to sows, 10(10) c.f.u. per day, during the period from 1 week before expected farrowing until 1 week after farrowing. Fecal samples from the sows and samples of litter were collected for bacteriological examination together with swabs from the pens, the skin of the sows, and from the rectum of the piglets. The test strains were only excreted in relatively low amounts in the feces of the sows, approximately 10(3)-10(6) c.f.u. per gram. They were not able to displace the normal lactic acid bacterial flora in the sows nor were they transmitted to the intestinal tract of the piglets to any significant extent. After the last administration the test strains disappeared from both feces, skin, and environment, indicating that no permanent colonization had taken place, although considerable differences in duration of persistence were noticed between test strains.
在给母猪投喂乳酸菌菌株后，研究了这些菌株在环境和新生仔猪中的传播情况。在预计分娩前1周直至分娩后1周期间，将耐利福平的细菌菌株以每天10(10) c.f.u.的剂量投喂给母猪。收集母猪的粪便样本、窝样本以及来自猪舍、母猪皮肤和仔猪直肠的拭子进行细菌学检查。测试菌株仅以相对较低的数量排泄在母猪粪便中，每克约10(3)-10(6) c.f.u.。它们无法取代母猪体内的正常乳酸菌菌群，也未在任何显著程度上传播到仔猪的肠道。在最后一次给药后，测试菌株从粪便、皮肤和环境中消失，表明没有发生永久性定植，尽管不同测试菌株在持续时间上存在相当大的差异。
