De Jong Z, Anaya Y, Pontonnier F, Ducassé J L, Izard P, Bloom E, Rougé D
Service d'Urologie, CHU Rangueil, Toulouse.
Ann Urol (Paris). 1992;26(6-7):364-7.
The authors present eight cases of Fournier's gangrene treated from 1987 to 1989 (3 years). There was no discernable cause for 5 patients (62.5%). Immediate aggressive surgical debridement of all necrotic tissue was performed. Intravenous antibiotics and resuscitation fluid and hyperbaric oxygenation were also administered to all patients. Skin grafting was performed for 4 patients (40%), 3 weeks after surgical debridement. One patient died (12.5%) and 2 subsequently developed an urethral stricture. Etiology, treatment and outcome of Fournier's gangrene are discussed and the results of the study are compared to other studies. This disease is still serious, its pathogenesis is not completely elucidated, but when immediate adequate treatment is performed, the outcome is generally favourable.
作者介绍了1987年至1989年(3年)间治疗的8例福尼尔坏疽病例。5例患者(62.5%)病因不明。对所有坏死组织立即进行积极的手术清创。所有患者均接受静脉抗生素、复苏液和高压氧治疗。4例患者(40%)在手术清创3周后进行了皮肤移植。1例患者死亡(12.5%),2例随后出现尿道狭窄。讨论了福尼尔坏疽的病因、治疗和结果,并将研究结果与其他研究进行了比较。这种疾病仍然很严重,其发病机制尚未完全阐明,但如果立即进行充分治疗,结果通常是良好的。