福尼尔坏疽：对41例患者的回顾性临床研究
Fournier's gangrene: a retrospective clinical study on forty-one patients.
作者信息
Ayan Fadil, Sunamak Oguzhan, Paksoy Sabri M, Polat Semra S, As Abdullah, Sakoglu Nevin, Cetinkale Oguz, Sirin Feridun
机构信息
Department of General Surgery, Cerrahpasa Medical School, Istanbul, Turkey.
出版信息
ANZ J Surg. 2005 Dec;75(12):1055-8. doi: 10.1111/j.1445-2197.2005.03609.x.
BACKGROUND
Fournier's gangrene, first described by Dr Jean Alfred Fournier in 1883, still has a high mortality rate. The prognosis and outcome of such patients were analysed.
METHODS
Forty-one patients with Fournier's gangrene were reviewed on the parameters of age, sex, aetiological agents, predisposing factors, treatment modalities and outcomes.
RESULTS
Although early intervention and careful treatment was carried out, nine of 41 patients (21.9%) died as a result of complications of septicemia. Among the treatment modalities, there were extensive debridement, drainage, excisions of the skin and fascia, colostomy procedure, extensive antibiotic treatment and hyperbaric oxygen therapy. Although a combination of different treatment modalities were used, the mortality rate was 21.9%.
CONCLUSIONS
Fournier's gangrene is still a severe disease. Today, hyperbaric oxygen treatment is very effective in the treatment of this disease.
背景
1883年让·阿尔弗雷德·富尼耶医生首次描述了福尼尔坏疽，其死亡率至今仍很高。对这类患者的预后和结局进行了分析。
方法
对41例福尼尔坏疽患者的年龄、性别、病因、诱发因素、治疗方式和结局等参数进行了回顾。
结果
尽管进行了早期干预和精心治疗，但41例患者中有9例（21.9%）因败血症并发症死亡。治疗方式包括广泛清创、引流、皮肤和筋膜切除、结肠造口术、广泛抗生素治疗和高压氧治疗。尽管采用了不同治疗方式的组合，但死亡率仍为21.9%。
结论
福尼尔坏疽仍然是一种严重疾病。如今，高压氧治疗对该病的治疗非常有效。
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