Entholzner E, Felber A, Mielke L, Hargasser S, Breinbauer B, von Hundelshausen B, Hipp R
Institut für Anästhesiologie der Technischen Universität München.
Anasthesiol Intensivmed Notfallmed Schmerzther. 1992 Dec;27(8):473-6. doi: 10.1055/s-2007-1000341.
Capnometers measure carbon dioxide (CO2) in inspired and expired air. Under physiological conditions end-tidal CO2 (peCO2) measurements closely reflect arterial pCO2 (paCO2). End-tidal CO2 concentration has been found to correlate with cardiac output in animal models and in clinical studies with cardiac arrest during cardiopulmonary resuscitation (CPR). In the present study in 23 cases of CPR end-tidal CO2 concentrations were registered during precordial compression with a transportable, battery-carried capnometer. In 7 cases of successful CPR mean concentrations of end-tidal CO2 were higher than in unsuccessful CPR (13 +/- 7 mmHg versus 8 +/- 6 mmHg). No statistical significance was found. In case of successful CPR there was a sudden rise in end-tidal CO2 up to 54 +/- 6 mmHg, indicating satisfactory spontaneous circulation. With capnometry it is possible to assess the efficacy of precordial compression during resuscitation and the return of spontaneous circulation in cardiopulmonary arrest.
二氧化碳监测仪可测量吸入气和呼出气中的二氧化碳（CO₂）。在生理条件下，呼气末二氧化碳（peCO₂）测量值与动脉血二氧化碳分压（paCO₂）密切相关。在动物模型以及心肺复苏（CPR）期间发生心脏骤停的临床研究中，已发现呼气末二氧化碳浓度与心输出量相关。在本研究中，使用便携式、电池供电的二氧化碳监测仪对23例CPR患者在胸外按压期间的呼气末二氧化碳浓度进行了记录。在7例CPR成功的病例中，呼气末二氧化碳的平均浓度高于CPR未成功的病例（13±7 mmHg对8±6 mmHg）。未发现统计学意义。在CPR成功的病例中，呼气末二氧化碳会突然升高至54±6 mmHg，表明自主循环良好。通过二氧化碳监测法，可以评估复苏期间胸外按压的效果以及心肺骤停时自主循环的恢复情况。
