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[诊断性辐射剂量诱发甲状腺癌的风险估计(作者译)]

[Risk estimation for thyroid cancer induced by diagnostic radiation doses (authors transl)].

作者信息

Schmitz-Feuerhake I, Bätjer K, Prévôt H

出版信息

Rofo. 1978 May;128(5):622-7. doi: 10.1055/s-0029-1230916.

DOI:10.1055/s-0029-1230916
PMID:149077
Abstract

Cancer of the thyroid has been detected as a late consequence of irradiation mainly for benign diseases. A survey of data from several investigators shows a strong correlation between incidence and thyroid dose. The result of a risk estimation for irradiated children assuming a linear non-threshold dose response is 60 cancers per 10(6) per rem in 20 years following irradiation. There is no evidence that adults will be much less sensitive. Radiation risks for the thyroid should be considered in nuclear medicine, because the diagnostic use of radioiodine leads to organ doses which are comparably high.

摘要

甲状腺癌已被发现是主要因良性疾病接受辐射后的晚期后果。对几位研究者的数据调查显示,发病率与甲状腺所受剂量之间存在密切关联。假设剂量反应呈线性无阈值,对受辐照儿童进行风险估计的结果是,辐照后20年内每10⁶人每拉德有60例癌症发生。没有证据表明成年人的敏感性会低很多。在核医学中应考虑甲状腺的辐射风险,因为放射性碘的诊断性应用会导致相当高的器官剂量。

相似文献

1
[Risk estimation for thyroid cancer induced by diagnostic radiation doses (authors transl)].[诊断性辐射剂量诱发甲状腺癌的风险估计(作者译)]
Rofo. 1978 May;128(5):622-7. doi: 10.1055/s-0029-1230916.
2
Incidence of malignant thyroid tumors in humans after exposure to diagnostic doses of iodine-131. II. Estimation of thyroid gland size, thyroid radiation dose, and predicted versus observed number of malignant thyroid tumors.
J Natl Cancer Inst. 1980 Dec;65(6):1221-4.
3
Cancer risks after diagnostic doses of 131I with special reference to thyroid cancer.诊断剂量的131I后的癌症风险,特别提及甲状腺癌。
Cancer Detect Prev. 1991;15(1):27-30.
4
Incidence of malignant thyroid tumors in humans after exposure to diagnostic doses of iodine-131. I. Retrospective cohort study.诊断剂量的碘-131照射后人类甲状腺恶性肿瘤的发病率。I. 回顾性队列研究。
J Natl Cancer Inst. 1980 May;64(5):1055-9.
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[Radiation exposure of patients during diagnostic application of radionuclides].[放射性核素诊断应用过程中患者的辐射暴露]
Strahlenschutz Forsch Prax. 1982;23:79-94.
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Risk of thyroid cancer after exposure to 131I in childhood.童年时期接触碘-131后患甲状腺癌的风险。
J Natl Cancer Inst. 2005 May 18;97(10):724-32. doi: 10.1093/jnci/dji129.
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Thyroid radiation absorbed dose from diagnostic procedures in U.S. population.美国人群诊断程序所致甲状腺辐射吸收剂量。
Radiology. 1985 Jul;156(1):183-5. doi: 10.1148/radiology.156.1.2988011.
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Properties, production, and clinical uses of radioisotopes of iodine.碘放射性同位素的性质、生产及临床应用。
CRC Crit Rev Clin Radiol Nucl Med. 1975 Feb;6(1):81-111.
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Indications for thyroid surgery. Panel discussion.甲状腺手术的适应症。小组讨论。
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[The effect of ionizing radiation on the thyroid].[电离辐射对甲状腺的影响]
Probl Endokrinol (Mosk). 1991 Jul-Aug;37(4):64-7.

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