Ransmayr G, Künig G, Gerstenbrand F
University Clinic of Neurology, Innsbruck, Austria.
J Neural Transm Suppl. 1992;38:129-40.
The article summarizes historical aspects and current concepts of the treatment of Parkinson's disease. Antiparkinsonian therapy varies with the progression of the disease, age and clinical subtypes. Levodopa, anticholinergic substances, direct dopamine agonists, amantadine, L-deprenyl are used to treat motor symptoms of Parkinson's disease. Novel substances and therapeutic concepts are currently investigated. Treatment of non-motor symptoms of Parkinson's disease and supportive therapies are discussed in the article.
本文总结了帕金森病治疗的历史方面和当前概念。抗帕金森病治疗因疾病进展、年龄和临床亚型而异。左旋多巴、抗胆碱能物质、直接多巴胺激动剂、金刚烷胺、L-司来吉兰用于治疗帕金森病的运动症状。目前正在研究新型物质和治疗概念。本文还讨论了帕金森病非运动症状的治疗和支持性疗法。
