Leinonen U I, Jalonen H U, Vihervaara P A, Laine E S
Orion Corporation Farmos, Turku, Finland.
J Pharm Sci. 1992 Dec;81(12):1194-8. doi: 10.1002/jps.2600811214.
The lubrication properties of two commercial-grade magnesium stearates were studied. Their moisture contents and crystal structures were similar. There were minor differences in their fatty acid composition, but the differences did not affect the lubrication properties. The lubrication properties correlated with particle size distributions and specific surface area. The effect of these parameters was further studied with unmilled and milled chemically pure magnesium stearate. Milling decreased the particle size and increased the specific surface area. In both cases, the batch with a smaller particle size and larger specific surface area had considerably better lubricity.
研究了两种商业级硬脂酸镁的润滑性能。它们的水分含量和晶体结构相似。它们的脂肪酸组成存在微小差异,但这些差异并未影响润滑性能。润滑性能与粒度分布和比表面积相关。用未研磨和研磨的化学纯硬脂酸镁进一步研究了这些参数的影响。研磨减小了粒径并增加了比表面积。在这两种情况下,粒径较小且比表面积较大的批次具有明显更好的润滑性。