Ault H K, Hoffman A H
Department of Mechanical Engineering, Worcester Polytechnic Institute, MA 01609.
J Biomech Eng. 1992 Feb;114(1):142-6. doi: 10.1115/1.2895438.
A micromechanical model of fibrous soft tissue has been developed which predicts upper and lower bounds on mechanical properties based on the structure and properties of tissue components by Ault and Hoffman [3, 4]. In this paper, two types of biological tissue are modeled and the results compared to experimental test data. The highly organized structure of rat tail tendon is modeled using the upper bound aggregation rule which predicts uniform strain behavior in the composite material. This model fits the experimental data and results in a correlation coefficient of 0.98. Applied to cat knee joint capsule, the lower bound aggregation rule of the model correlates with the data and predicts uniform stress within this more loosely organized tissue structure. These studies show that the nature of the interactions between the components in tissue differs depending upon its structure and that the biomechanical model is capable of analyzing such differences in structure.
奥尔特和霍夫曼[3,4]开发了一种纤维软组织的微观力学模型，该模型基于组织成分的结构和特性预测力学性能的上下限。本文对两种生物组织进行了建模，并将结果与实验测试数据进行了比较。大鼠尾腱高度有序的结构采用上限聚集规则进行建模，该规则预测复合材料中的均匀应变行为。该模型与实验数据拟合，相关系数为0.98。将该模型应用于猫膝关节囊，其下限聚集规则与数据相关，并预测了这种组织结构较松散的组织内的均匀应力。这些研究表明，组织中各成分之间相互作用的性质因其结构而异，并且生物力学模型能够分析这种结构差异。
